Markers of platelet activation and apoptosis in platelet concentrates collected by apheresis
Renata Procházková, Ctirad Andrýs, Lenka Hubácková, Jan Krejsek
DOI: 10.1016/j.transci.2007.03.015
Klíčová slova: Adult, Apoptosis, Biological Markers, Blood Component Removal, Blood Donors, Blood Platelets, Blood Preservation, Cell Separation, Female, Humans, Male, Middle Aged, Platelet Activation, Platelet Count, Prospective Studies, Reference Values, Reproducibility of Results
Anotace:
BACKGROUND: A product with well-preserved haemostatic function of platelets is the ultimate goal of platelet concentrate production. However, platelet activation and apoptosis are induced by both collection and storage of platelet concentrates. BACKGROUND: A product with well-preserved haemostatic function of platelets is the ultimate goal of platelet concentrate production. However, platelet activation and apoptosis are induced by both collection and storage of platelet concentrates. BACKGROUND: A product with well-preserved haemostatic function of platelets is the ultimate goal of platelet concentrate production. However, platelet activation and apoptosis are induced by both collection and storage of platelet concentrates. BACKGROUND: A product with well-preserved haemostatic function of platelets is the ultimate goal of platelet concentrate production. However, platelet activation and apoptosis are induced by both collection and storage of platelet concentrates.